as cool of an experience as this was and as interesting as these things are, it’s always important to acknowledge the bad along with the good. Henrietta Lacks’ cells revolutionized so many areas of research, but she deserved so much better.
working with these cells today just really reminded me of the duality of many scientific developments. many things have come with great cost and harm and i think that’s something important to keep in mind.
if you aren’t familiar with the story of Henrietta Lacks, i highly recommend looking her up. there’s a book about her live (the immortal life of henrietta lacks) that’s very illuminating.
Monday december 13
hello my lovelies! sorry for being so absent, the ib has been crushing me haha (laughing to avoid crying) so I have not been able to be active on social media. you know, the future doctor agenda is not quite fun if you ignored biology for three years so I hope you understand <3
school ends in 2 days (thank the gods) so I need to doooo a lot of things.
🎧 - indiana (hombres g)
📚 - chemistry textbook
THINGS I NEED TO DO FOR TOMORROW
finish my presentation of gender roles for spanish
study for my chem final
send emails to my glopol teacher
prepare my microbiology lab
by Edward Jones on yt
photo source-The MacroClub Project (Myxomycetes)
Slime Mold
Mycologists, mostly from Latin America, established the term “funga” five years ago. It refers to the levels of diversity of fungi in any given place, and is analogous to “flora and fauna”, which refer to plants and animals. Unlike flora and fauna, it is not a Latin term but was chosen because it is morphologically similar. “Just like mycelium, mycologically inclusive language will spread unseen but profound [sic], permeating public consciousness (and policy) to acknowledge fungi’s vital role in the grand web of life on and in Earth,” it said. Government agencies in Australia, Brazil, Iceland and elsewhere have picked up on the word. Its creation and use reflects an increasing appreciation of the fungal kingdom and how it connects the plant world through an underground mycelial network.
[...]
Giuliana Furci and the biologist and author Merlin Sheldrake wrote: “Accounts of the living world that do not include fungi are accounts of a world that doesn’t exist. “Fungi have long sustained and enriched life on Earth. We are unthinkable without them, and yet we are only just beginning to understand the intricacies of fungal lives. It’s time we give them the attention they deserve."
Seriously, genetics is weird.
I was reading one paper on long noncoding RNAs and there's this one part that just really stood out to me.
So to catch everyone up, genetic data is stored as DNA. Then parts of it go through a process called transcription to build a strand of RNA. Certain RNAs get translated into proteins, but there are noncoding RNAs that don't make proteins but instead do a secret second thing (and I mean secret cause there are tons of ncRNAs that no one knows what they do). long noncoding RNAs are just noticeably longer than average.
Anyway, one lncRNA mentioned in the paper is called WINCR1. When the researchers managed to block it from being used, they noted that cells lost the ability to divide and there was one particular gene GADD45B, which is responsible for triggering apoptosis, was more common in the cells.
So my guess is one of WINCR1's jobs is to just confirm to the self-destruct system that the DNA isn't broken. Like, it being transcribed essentially tells the cell that that part of the DNA is still working and it can then go and turn off the kill switch.
So I guess cells are just designed to kill themselves as their default setting and WINCR1 is the drinking bird pressing the Y key to tell the system to not just blow up.